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Dun Research Group – Temple University

The Dun research group is interested in the development, application, and commercialization of novel nanoprobes that enable nanosurgery of single cells and sub-cellular compartments.  Specifically, carbon-based nanoprobes offer significant advantages over existing commercial technologies such as probe durability, minimally damaging to cells, and multifunctional analytic capabilities.  In collaboration with several multidisciplinary groups from Temple University, Drexel University, and the University of Pennsylvania, the Dun group utilizes nanoprobes for intracellular delivery and the measurement of cell signals to study cellular functions.  NTI-funded research explores using carbon nanopipettes (CNPs) for the real-time detection of intracellular molecules through fluorescent microscopy and surface enhanced Raman spectroscopy (SERS).  Long term, the Dun group aims to develop novel tools and techniques to analyze single and multiple cells for use in pharmacology and physiology.

 
For more information about the Dun research group visit their website.

Why Is Small So Big?

Nanotechnology deals with products and processes that are measured in almost unbelievably small increments called “nanometers”—one billionth of a meter.

At the nanoscale, materials differ from larger objects in their physical, chemical and biological properties; therefore, they lend themselves to new and improved materials, systems and devices. Nanotechnology is behind the development of such diverse advancements as:

  1. Drug Delivery
  2. Biofiltration and Separation sciences
  3. Improved coatings for medical devices

Thanks to rapid advances in this exciting new field, we now have the tools and talents to manipulate materials on the molecular scale—a technology literally changing the world as we know it.