The Dun research group is interested in the development, application, and commercialization of novel nanoprobes that enable nanosurgery of single cells and sub-cellular compartments. Specifically, carbon-based nanoprobes offer significant advantages over existing commercial technologies such as probe durability, minimally damaging to cells, and multifunctional analytic capabilities. In collaboration with several multidisciplinary groups from Temple University, Drexel University, and the University of Pennsylvania, the Dun group utilizes nanoprobes for intracellular delivery and the measurement of cell signals to study cellular functions. NTI-funded research explores using carbon nanopipettes (CNPs) for the real-time detection of intracellular molecules through fluorescent microscopy and surface enhanced Raman spectroscopy (SERS). Long term, the Dun group aims to develop novel tools and techniques to analyze single and multiple cells for use in pharmacology and physiology.
For more information about the Dun research group visit their website.
NTI: Signs of Success
NTI research programs have been extremely successful at publishing in peer-reviewed journals, resulting in more than 820 articles.
In addition, NTI researchers have been awarded more than 200 federal grants totaling more than $150 million.